Cookies help us deliver our services. By using our services, you agree to our use of cookies. Learn more

Corticobasal Degeneration

What is Corticobasal Degeneration?

Corticobasal Degeneration is a rare neurological disease characterized by atrophy of multiple areas of the brain, including the cerebral cortex and basal ganglia.

 

Corticobasal Degeneration is a rare neurological disease characterized by atrophy of multiple areas of the brain, including the cerebral cortex and basal ganglia.
Acknowledgement of Corticobasal Degeneration has not been added yet.
4.0http://www.orpha.net
Synonyms for Corticobasal Degeneration has not been added yet.
The cause of corticobasal degeneration is unknown. Previous cases suggest that there may be a familial connection for individuals with this disease. A genetic cause is suggested.
Corticobasal degeneration is characterized by limb apraxia, where individuals are unable to perform familiar movements on command. Amnesia and “frontal-executive” mental deficits, such as judgement impairment or increased distractibility, are possible cognitive abnormalities. Eye movements may be restricted in horizontal movement and upgaze. Dystonia and myoclonus, involuntary muscle contractions, cortical sensory loss, the loss of sensitivity, and rigidity, are also symptoms. It is common that cognitive and behavioural symptoms present before motor symptoms. Initial physical symptoms usually appear in individuals in their 60s, in the form of poor coordination, or difficulty completing everyday tasks.
Symptoms and signs of corticobasal degeneration are frequently also caused by other neurodegenerative diseases, so “corticobasal syndrome” is used as the name of the clinical diagnosis. At autopsy, the term “corticobasal degeneration” is only used for those meeting the neuropathological criteria.
Diagnostic tests of Corticobasal Degeneration has not been added yet
There is no known cure for corticobasal degeneration, so treatment focuses on managing symptoms of CDS. The patient will generally be taken off medications that may lead to cognitive impairment, and given vitamin E and antioxidants. He or she will be given medication to manage pain, rigidity, and dystonia. The patient may also be treated for depression. Speech, physical, and occupational therapy can be helpful in maintaining endurance and communication. Affected individuals might also want counseling regarding disability and end-of-life care.
This disease is incurable and progressive. The average course of this disease is around 7 years. Death is usually caused by complications of the disease, most often pneumonia.
Name Description
C It is crucial for individuals with Cushing’s syndrome to not push themselves too hard physically, eat healthily, and monitor their mental health. Cognitive issues resulting from Cushing’s syndrome may improve through mental exercises such as Sudoku. Pain can be alleviated with low-impact exercise, hot baths, and massages.
References of Corticobasal Degeneration has not been added yet.
Garrymac Created by Garrymac
Last updated 13 Sep 2016, 11:27 PM

Posted by Garrymac
13 Sep 2016, 11:27 PM

Hi , never been a member of a forum before so here goes,,,my wife Janice (55) is now in a hospital bed at home and in the latter stages of Corticobasal degeneration...6 weeks ago we were going for runs in the car and for dinner etc,although I had to physically feed her etc..then she got constipated after discharging more than ample faeces ...along with her 6 monthly fall ...she ended up in hospital to clear the constipation and on getting X rayed there was no damage to her after the fall...she now is totally helpless at home getting liquidised food and incontinent ....all in the space of 6 weeks...carers 4 times a day ...my main worry at the moment is that she maybe in pain as for about 6-7 hours every day she looks like she's possessed by a demon and dizapam etc only relief it briefly...she's aggressive and tries to hit out then out of the blue she calms down and becomes placid and loving ...I'd like to ask has anyone on here ever experienced the likes of this with their loved one...thanks for reading this Garry

Progression of CBD Created by Rosiemama
Last updated 6 Nov 2012, 03:18 AM

Posted by grammyd1952
6 Nov 2012, 03:18 AM

i have had cbdg diagnosed 1 year ago, i have had physical therapy, it does not work, unless you and the patient are100^ committed. i am not that committed someone suggested i start on longvida, fish oil, vit d, c, b, ans o2q10. if you really want the dose let me know

Posted by Rosiemama
17 Dec 2010, 12:56 PM

Hello everyone My father-in-law was diagnosed with CBD in July after a few years of experiencing symptoms that puzzled all of his doctors. What stage are your loved ones in and how fast has this disease progressed for them? One of his arm's started jerking a few years ago, followed by loss of peripheral vision. A year and a half ago he had to stop driving because he could not keep the car in the proper lane. Now he can't read because he can't track the lines, he can't put his clothes on properly, he must use a walker because his sense of balance is very bad, and he has trouble using everyday items. He says he knows what he should do with them but he can't make his hands do what they should do. He is also cold almost all of the time. Does anyone have any suggestions or practical tips? Have you tried occupational therapy? Thanks, Rosiemama

Community External News Link
Title Date Link
Community Resources
Title Description Date Link

Clinical Trials


Cords registry

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, individuals and researchers to help in the advancement of research in over 7,000 rare diseases. The registry is free for patients to enroll and researchers to access.

Enrolling is easy.

  1. Complete the screening form.
  2. Review the informed consent.
  3. Answer the permission and data sharing questions.

After these steps, the enrollment process is complete. All other questions are voluntary. However, these questions are important to patients and their families to create awareness as well as to researchers to study rare diseases. This is why we ask our participants to update their information annually or anytime changes to their information occur.

Researchers can contact CoRDS to determine if the registry contains participants with the rare disease they are researching. If the researcher determines there is a sufficient number of participants or data on the rare disease of interest within the registry, the researcher can apply for access. Upon approval from the CoRDS Scientific Advisory Board, CoRDS staff will reach out to participants on behalf of the researcher. It is then up to the participant to determine if they would like to join the study.

Visit sanfordresearch.org/CoRDS to enroll.

Community Leaders

 

Expert Questions

Ask a question

Community User List

Wife of a patient

I'm Garry and would like to...
I have intrest to learn, to...
60, diagnosed 1 year ago wi...
I am the Director of Outrea...
Wife of a patient

Start a Community


Don't See Your Condition On Rareshare?

Start your own! With a worldwide network of 8,000 users, you won't be the only member of your community for long.

FAQ


Have questions about rareshare?

Visit our Frequently Asked Questions page to find the answers to some of the most commonly asked questions.

Discussion Forum

Garrymac

Created by Garrymac | Last updated 13 Sep 2016, 11:27 PM

Progression of CBD

Created by Rosiemama | Last updated 6 Nov 2012, 03:18 AM


Communities

Our Communities

Join Rareshare to meet other people that have been touched by rare diseases. Learn, engage, and grow with our communities.

FIND YOUR COMMUNITY
Physicians

Our Resources

Our rare disease resources include e-books and podcasts

VIEW OUR EBOOKS

LISTEN TO OUR PODCASTS

VIEW OUR GUIDES

Leaders

Our Community Leaders

Community leaders are active users that have been touched by the rare disease that they are a part of. Not only are they there to help facilitate conversations and provide new information that is relevant for the group, but they are there for you and to let you know you have a support system on Rareshare.