I'm HAE III, subtyped as post menopause exacerbated. UGH. It got so much worse after menopause. I now have weekly abdominal attacks, have gone through millions of dollars worth of special medications, ER visits, diagnostics, etc. Am currently using icatibant/Firazyr when the attacks start. It's helping a lot. No more pain meds. Fingers crossed that it keeps working. Also have Kalbitor/Ecallentide as a rescuer med too, but it cannot be self-administered, and so far the Firazyr, a Bradykinin inhibitor seems to be working better. No side effects of being really tired after dosing. Thank God I have a pretty good insurance plan.