I too suffered from debilitating migraines. However, recently my Dr. slowed down the infusion rate, added prednisone one hour before and 24 hours after my infusion and also increased the amount of fluids I receive intravenously immediately following IVIG. This new protocol has eliminated my migraines. I still suffer from headaches, fatigue and some nausea as well as hypertension for several days following the infusion but with the change in protocol I have not suffered from migraines. I also make sure to drink a lot of water the day before and during IVIG. I also find hydrating and eating a salty meal the night before helps with the headaches and eases the nurses ability to start a line.
I receive 30 grams of gammunex C 10 % every 14-21 days followed by a bag of fluids for one hour ( I think it's dextrose and sonething else). I take extra strength Tylenol, Claritin and prednisone 30 minutes prior to infusion and prednisone 24 hours after the infusion. In my case, Advil is much more effective than Tylenol in treating my headaches but i am not supposed to take it.
The IVIG and one hour bag of fluids takes approximately 8 1/2 to 9 hours.
I have been receiving IVIG at the infusion center at a major hospital in the Detroit area for 9 years.
I was receiving 30 grams of flebogamma 5% but they discounted it. So now I'm on gammunex C 10 %.
I also found that switching from Benadryl to Claritin makes me less sleepy and has eliminated the hungover feeling that I was experiencing for days following the IVIG.
Wishing good health to all!