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Psoriasis

What is Psoriasis?

Psoriasis is a chronic autoimmune system condition that is commonly considered an inflammatory skin disease. Psoriasis causes a rapid expansion of skin cells that leads to the formation of painful and itchy red scales on the skin, or plaques. Plaques are thick, red, scale like skin caused by buildup of dead skin cells. Healthy skin cells takes about a month to make new skin cells and shed old cells. In psoriasis, the process is accelerated. The overactive immune system causes inflammation. Inflammation causes the skin cells to produce at a rapid rate, approximately seven times faster than healthy skin cells. The rapidly produced skin cells pile up and get pushed to the surface because the body cannot shed them as fast as they are produced. The skin builds up, thickens and becomes red, itchy, inflamed, raised and/or flaky.

 

Psoriasis is a chronic autoimmune system condition that is commonly considered an inflammatory skin disease. Psoriasis causes a rapid expansion of skin cells that leads to the formation of painful and itchy red scales on the skin, or plaques. Plaques are thick, red, scale like skin caused by buildup of dead skin cells. Healthy skin cells takes about a month to make new skin cells and shed old cells. In psoriasis, the process is accelerated. The overactive immune system causes inflammation. Inflammation causes the skin cells to produce at a rapid rate, approximately seven times faster than healthy skin cells. The rapidly produced skin cells pile up and get pushed to the surface because the body cannot shed them as fast as they are produced. The skin builds up, thickens and becomes red, itchy, inflamed, raised and/or flaky.

Acknowledgement of Psoriasis has not been added yet.

Psoriasis affects the lives of 125 million people worldwide. The estimated prevalence of Psoriasis is 2 to 3 percent of the global population.

Anyone can develop psoriasis. It is most common in adults, but it can occur in children as well. Women and men have equal risk of developing psoriasis.

There is a genetic link present. If a family member has psoriasis, one is more likely to develop psoriasis.

Synonyms for Psoriasis has not been added yet.

Psoriasis is a chronic autoimmune disease. The body’s own immune system becomes overactive and attacks normal healthy cells in the body. In healthy individuals, a type of white blood cell called T-cells protect the body against foreign substances, including bacteria and viruses, by attacking target molecules called antigens. In psoriasis, T-cells are unusually overactive, inadvertently invading healthy tissues and initiating an immune response.

Psoriasis can be a triggered condition. Triggers for psoriasis are stress, injury to skin, medications, infection, allergies, and diet. Medications that can trigger psoriasis are lithium, anti-malarials, propranolol, quinidine and indomethacin.

Psoriasis symptoms vary from individuals and depend on the type. Zones of psoriasis can be as small as scales on the scalp or cover the entire body. More common symptoms are red and scaly patches, dry and cracked skin, itching, burning, soreness, pitted nails, and swollen joints. Not all affected individuals will experience all of these symptoms. Additionally, psoriasis can accompany many other conditions, such as psoriatic arthritis, cardiovascular problems, obesity, high blood pressure, diabetes and depression.

There are several types of psoriasis with their own distinct characteristics and symptoms.

1.      Plaque Psoriasis is the most common type of psoriasis. Symptoms are raised, inflamed, red lesions that are covered with scaly, silvery plaques. They are commonly located on the elbows, knees, scalp, back and lower back. It can also be found in other areas such as the nails, legs, hands, genitals and breasts.

2.      Guttate Psoriasis is childhood or young adulthood psoriasis. There are small, pink, spots. They are not thick and scaly, like plaques. They are commonly found on the torso, arms and legs.

3.      Pustular Psoriasis is most common in adults. They can be only on one area of the body or all over the body. They consist of yellow pustular blisters that are not infectious. They can be found around the hands and feet only or all over the body.

4.      Inverse Psoriasis is typically located on the skin folds. They are bright red lesions that are smooth and shiny. They are located on the skin folds of the armpits, neck, groin, under the breasts, genitals and buttocks.

5.      Erthyrodemric Psoriasis is the most severe form of psoriasis. It affects the entire body. The spots are red, inflamed skin with scales shedding in sheets.

At times, psoriasis can be hard to diagnose. It appears similar to a variety of other skin diseases. It can be clinically diagnosed by taking a skin biopsy and observing the skin under a microscope. It is typically diagnosed by a physical examination and taking into consideration the individual’s medical history, family history, and skin and nail appearance.

A skin biopsy is the main diagnostic test used. A local anesthetic is applied to the skin site and a small sample of skin is removed. The small sample of skin, the biopsy, is examined under a microscope to identify the type and severity of the psoriasis.

There is no cure at this time for psoriasis, but symptoms can be controlled. Many individuals can live in remission or minimize flare ups with several types and combinations of treatment. In mild to moderate cases topical treatment alone, with creams and ointment, are applied directly to the skin. In  moderate to  severe cases, topical treatment can be combined with light. Light therapy is a treatment with natural or artificial ultraviolet (UV) light that emit UV rays directly onto the skin to help slow the growth of excess skin.  In treatment resistant cases or severe cases, oral medication or injected drugs are prescribed. 

Psoriasis is not life-threatening, but is chronic with no distinct cure. Symptoms are debilitating, painful, embarrassing and a nuisance. Maintaining symptom control is the treatment goal.

Eating foods that minimize inflammation can be beneficial. Foods that help fight inflammation include fruits, vegetables, fish, low-fat dairy products, whole grains and lean meat. Foods that can contribute to increased inflammation include fatty meats, refined or processed foods and high-fat dairy foods.

Exercising to maintain a healthy weight can also decrease the severity of psoriasis. Individuals who are obese typically have more severe psoriatic symptoms.

UPDATE -- Community Details Created by RareshareTeam
Last updated 4 Feb 2020, 07:49 PM

Posted by RareshareTeam
4 Feb 2020, 07:49 PM

Hello all! Psoriasis community details has been update with the lastest treatments and additional information!

Community, share some of your experiences with managing psoriasis or treatment success & failures!

Chat soon!

What do you think of hemp cosmetics? Created by Martin88
Last updated 28 Jan 2010, 11:43 AM

Posted by Martin88
28 Jan 2010, 11:43 AM

Hi, I'm new here and I suffer from the same nasty problem for several years. I tried many things, something even helped me to alleviate psoriasis, but unfortunately did not cure. I saw you write about Dr. Bronner, I haven't tried it yet, but I've got a tip. On a net I stumbled on an online store cannabiscosmetics.com with special hemp cosmetics, produced from the seeds of Cannabis sativa that doesn't contain THC. I ordered a cream that has a high percentage of hemp oil, quite helps. Anyone with experience here?

Enbrel Created by dgcohen23
Last updated 10 Jul 2008, 11:50 PM

Posted by mummy2three
10 Jul 2008, 11:50 PM

michaelisserman ~ Keep us posted on your results. The peppermint is our favorite but, I would not suggest using it if you are broken out.

Posted by michaelisserman
10 Jul 2008, 10:26 PM

Thank you for the suggestion. I just picked up a bottle of Dr. Bronner's and will try it this week.

Posted by mummy2three
9 Jul 2008, 03:32 PM

I have had Psoriasis since I was a child and have tried just about everything. I did not try Enbrel though. One thing that has greatly helped me is Dr. Bronner's soaps. You can find it at most health food stores and grocery stores like Whole Foods. I have been using it for the past two years and have only had two separate breakouts. One from stress and the other I think from allergies. I would not stop the Enbrel if it is working but, I would give the soap a try.

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National Psoriasis Foundation

The National Psoriasis Foundation is a patient-driven, nonprofit organization that is the voice for the millions of Americans affected by psoriasis and psoriatic arthritis.

03/20/2017

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Cords registry

CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases. This program allows patients and researchers to connect as easily as possible to help advance treatments and cures for rare diseases. The CoRDS team works with patient advocacy groups, individuals and researchers to help in the advancement of research in over 7,000 rare diseases. The registry is free for patients to enroll and researchers to access.

Enrolling is easy.

  1. Complete the screening form.
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  3. Answer the permission and data sharing questions.

After these steps, the enrollment process is complete. All other questions are voluntary. However, these questions are important to patients and their families to create awareness as well as to researchers to study rare diseases. This is why we ask our participants to update their information annually or anytime changes to their information occur.

Researchers can contact CoRDS to determine if the registry contains participants with the rare disease they are researching. If the researcher determines there is a sufficient number of participants or data on the rare disease of interest within the registry, the researcher can apply for access. Upon approval from the CoRDS Scientific Advisory Board, CoRDS staff will reach out to participants on behalf of the researcher. It is then up to the participant to determine if they would like to join the study.

Visit sanfordresearch.org/CoRDS to enroll.

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UPDATE -- Community Details

Created by RareshareTeam | Last updated 4 Feb 2020, 07:49 PM

What do you think of hemp cosmetics?

Created by Martin88 | Last updated 28 Jan 2010, 11:43 AM

Enbrel

Created by dgcohen23 | Last updated 10 Jul 2008, 11:50 PM


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