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Ledderhose's Disease

What is Ledderhose's Disease?

Ledderhose's Disease is a rare disorder consisting of non-malignant thickening of the feet's deep connective tissue.

 

Ledderhose's Disease is a rare disorder consisting of non-malignant thickening of the feet's deep connective tissue.
Acknowledgement of Ledderhose's Disease has not been added yet.
Prevalence Information of Ledderhose's Disease has not been added yet.
Synonyms for Ledderhose's Disease has not been added yet.
Cause of Ledderhose's Disease has not been added yet.
Pain, Burning, Tingling
Diagnosis of Ledderhose's Disease has not been added yet.
Diagnostic tests of Ledderhose's Disease has not been added yet
Treatments of Ledderhose's Disease has not been added yet.
Prognosis of Ledderhose's Disease has not been added yet.
Tips or Suggestions of Ledderhose's Disease has not been added yet.
References of Ledderhose's Disease has not been added yet.
Diagnostician Created by Inger
Last updated 31 Jul 2010, 10:12 PM

Posted by Inger
31 Jul 2010, 10:12 PM

Can anyone name a doctor, in Canada or the States or anywhere, who can diagnose Ledderhose or Dupuytren's in the feet? Please!

Treatment Options Besides Surgery Created by ThePhoenixLives
Last updated 21 May 2010, 09:32 PM

Posted by Lumpyfeet
21 May 2010, 09:32 PM

Like you, I consider myself well informed in Plantar Fibromatosis. If you think you are disappointed, you should come to Canada, where they still do not have Cryo for Podiatric surgeries. I have a theory similar to you, that this is auto immune related. I think that the nodules are actually stimulated by exercise. They are hyper tissue growth, like a benign cancer. Its the body's hyper response perhaps to injury. When mine started, I was just starting my nursing career and on my feet for 12 hours a day. I walked everywhere. Now, after 16 years, 2 complete resections both feet, and now cryo, I am lucky I am still walking on my own steam. So far, my faith is in the cryo, because as far as I know Xiaflex is not for Plantar Fibromas. I had cryo about 12 weeks ago, and it got me back walking and on less pain meds. Yes, grafting is known to discourage tumor regrowth, but the extensive recovery is not an option, as I have equal problems in both feet. I am glad that you are finding some options. I do not know if you are also part of the Plantar Fibromatosis web group on Yahoo, but there are more members and lots of info. Good Luck! Susan

Posted by ThePhoenixLives
18 Aug 2009, 10:14 PM

I'd like to know the treatment options considered by the members here. Please share what you're doing, other than surgery. Below is my own history with the disease. I'm a 46 year old woman with Ledderhose, diagnosed when I was 29 yrs old. My father has Dupuytren's. I am currently hobbling around on crutches as I had 3 tumors removed from my right foot two weeks ago; the size of tissue removed was about 2 1/2 to 3 inches long by 1 inch wide. This time (this is my third surgery with large Ledderhose tumors), I am being treated by a talented young Podiatrist/surgeon who used human tissue (grown in the lab) to replace the space of the tumors. This doctor has had very good success in zero repetition of the tumors after using the foreign skin (of course he also is taking a clean margin around the tumors as well, a well known technique to prevent reaccurance). I will say that I consider myself a near-expert in Ledderhose, since I have needed 3 surgeries in the past 17 years to live a semi-normal life. I have had Hashimoto's disease (thyroid-auto-immune) since I was 19 years old, but it was not treated until I was 38 years old, when I finally got very very sick. I also have the auto-immune variety of Arthritis. My endocrynologist (an extremely talented woman) knows nothing of Ledderhose. I WISHED that there was one doctor who could treat all of this auto-immune stuff (including Ledderhose, which I believe is auto-immune), but I have not found a doctor who could do this. So...the Podiatrist for Ledderhose, the Endocrynologist for the Hashimoto's, and the Rhumatologist for the arthritis. What no one has ever told me (because no one knows) is WHY. I will say that I am quite dissappointed that in the USA, the NIH (the National Institute of Health--the government agency for medical research) has put exactly ZERO dollars towards research of Ledderhose. Other tumors: I should note that I currently have fibroid tumors in my uterous and one of my lungs, and no doctor can tell me why. I do have an appt with a lung doc in Sep 09 to pursue diagnosis. Background: My first tumor was very large (left foot), and at the time I was an extremely fit 29 year old woman, a vegetarian (I do not believe that diet plays any part in Ledderhose) running 6 miles a day 6 days a week. The tumor went from a pea size to 2 inches in one month (left foot); surgery was the only option. The doc took a clean margin of tissue around the tumor. Tumor never reacurred in this foot. My second tumor was in 2004 (right foot), it was about 1/2 inch in diameter on the right foot. The doctor never took a clean margin around the tumor. Tumor reacurred in 2008, in multiples in right foot. Aug 2009 are latest tumors (3 of them) in the right foot (explained above).

Xiaflex Injections for Ledderhose Created by Loveboating2
Last updated 20 May 2010, 04:00 PM

Posted by peekaboo0419
20 May 2010, 04:00 PM

Dupuytrens Contracture has a website and gives information on XIAFLEX unfortunately it deals more with the chords not the nodules. So not an option for us. Please take a read though lots of great information. I have both Ledderhose in both feet and Dupuytrens in both hands. I am just a patient but have researched this alot and wished I would have prior to surgery. !!! I hope this helps you.

Posted by Loveboating2
20 Apr 2010, 09:44 PM

I was diagnosed with Plantar's Fibroma in 2003 with a tumor about the size of a pea in the right foot with no pain at the time. Since that time, I have a second tumor on the right foot and one large tumor on the left foot. I am now starting to experience pain when standing or walking for an extended length of time. My father had Dupuytren's Contracture in his hand and I guess passed the gene to me. I am now at a time where a decision needs to be made as to surgery or the new injection of Xiaflex. Does anyone know anything about this?

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Discussion Forum

Diagnostician

Created by Inger | Last updated 31 Jul 2010, 10:12 PM

Treatment Options Besides Surgery

Created by ThePhoenixLives | Last updated 21 May 2010, 09:32 PM

Xiaflex Injections for Ledderhose

Created by Loveboating2 | Last updated 20 May 2010, 04:00 PM


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