The MHE Research Foundation is always happy to assist MHE / MO / HME families in obtaining the medical information they need. Please feel free the to post your question and comments. Sincerely Sarah Ziegler The MHE Research Foundation Vice President & National Director of Research Executive Director, The MHE National Research Registry & Coordinator of Clinical Information Liaison Officer, University of Antwerp, Department of Genetics, Belgium Liaison Officer, Rizzoli Orthopaedic Institute, Genetics Unit, Bologna Italy

Our family has a B-12 deficiency and periphial neuropathy that seems to be associated with our HMO. Do you have any information about this? Laurie

I have not seen any direct research on the EXT genes that would connect 12 deficiency to MHE/MO/HME. Neuropathy has is seen in MHE patients. Periphial neuropathy this all depends of the context in the use of this term... Regards Sarah