First I apologize for my English!
I have a Clarkson syndrome evolving since several years. At first, the symptomatology was chronic, but gradually, crisis became more and more severe (since October 2017).
I am a nurse, and the swelling really complicated my practice, both in physical and intellectual requirements. I am in leave sick since April 2018.
In February 2017, although I didn’t had any risk factor, my blood test showed a systemic candidiasis. Since then, I took fluconazole for several months but the candidiasis is still evolving and very difficult to keep under control.
I noticed that the days before a SCLS crisis, in addition to sinusitis or flu syndrome, I am very tired, my body temperature goes down to 32 or 33°C, I am achy, need sugar, and in the same time the elimination begins to decrease ! ( I have the notion that Candida albicans needs sugar to survive and grow ?!)
In my case, the consumption of sugars seems to play a role with the occurrence of oedematous crisis.
I have been taking Fluconazole for several months and as soon as I stop it (or eat something too sweet), gradually oliguria starts again (and others symptoms follow). A serology was performed again this month. Candidiasis is still evolving despite of the Fluconazole.
I read a lot about the SCLS but I never found any publication reporting tests between SCLS and systemic candidiasis. However, Candidiasis could lead to an hypovolemia shock.
So do you think it could be a link between these two disorders ? (Candida albicans by itself, or a protein that it would produce etc)
I am so curious and would love to get your opinion on this subject !