Has anyone else made a miraculous recovery after receiving Rixan? My dlco was 39. After 2 years of Rixan my dlco is now 82 and I am off oxygen!!! 

Dear Sherryl,

Thank you for sharing your experience with the Antisynthetase syndrome
community members. We have found a review article published in the journal
Rheumatology that might give you some insight about the subject.

https://academic.oup.com/rheumatology/article-lookup/doi/10.1093/rheumatology/kew146

It is an overview of the use of Rituximab to treat inflammatory myopathies
(including dermatomyositis, polymyositis and antisynthetase syndrome) that did
not respond to conventional treatment. The authors have compiled data available in
the medical literature from different studies and have analyzed them combined. By
doing so, they have found that 78.3% (359/458 patients) that did not respond to
conventional therapies and were treated with Rituximab achieved some kind of
response (an improvement in at least one of the symptoms of the disease). They
pointed out, that the majority of patients with myositis-specific antibodies
(antibodies specific of autoimmune muscle disease) had a good response. Among
them, the patients with anti-Mi- 2 or anti-Jo1 antibodies showed a greater response.
This does not mean that Rituximab is going to be able to cure the disease, and in fact
there were some patients that did not show any improvement after the treatment.

We hope that you find this information useful.

The Rareshare Team

I've had recent success with Ritiximab. I had two infusions in August. My lung function improved from 57% to 72%. I have energy, no pain and feel a general sense of 'wellness'