Hello, I just joined this forum. I have MCTD for 7 years now and Im wandering what you guys found helps the symptoms? From medication I felt that plaquanil helps the most with joint pain. From supplements I felt probiotics such as l.acidophilus, l. Rhamnosus, and l.plantarum maybe help w fatigue.And primrose oil helps w fatigue too. Also do you feel better at any regular intervals? O feel completely normal one day a month! That the day Im supposed to get my period. One amazing thi g that helped was baclofen that im taking for GERD. I had horrible GERD and with the first pill of baclofen it was gone. What are your good experiences with medication or supplements?