Good Afternoon, I was wondering if any other Dent's patients have had elevated white blood cell counts? About a month ago my White Blood cell count, specifically my Eosinipihl White Blood Cells skyrocketed, which was discovered through my monthly blood work. After a ton of tests they still do not know what caused this, but feel it may have been related to allopurinol as after I stopped taking it, my levels started improving. If anyone has seen this occur, i'd be curious to hearing. I do not believe it is related to Dent's, but possibly medications taken.

Hi Jay. I hope you are doing well and that your levels are OK. I know Daniel takes similar meds to you, including allopurinol, I checked his lab history and I do not think he has ever had elevated eosiniphils, but, to be honest, I am wondering if they have ever checked them, as they are listed on the sheet but it is all blank. Or it says 0.0. Is it normal for the level to be zero? The doctor once took him off allopurinol when he was a teen, but I requested to put him back on it, because those two years Daniel's kidney functioned dropped more rapidly. Have you felt any symptoms/ill because of the high level of white blood cells?

As of my labs today, the numbers have now gone completely back to normal, so the allergist is pretty certain it was related to the allopurinol. As for the results, I think your correct in your assumption that this is not something the doctors normally test for. In my monthly labs they test for overall White Blood count, so when they saw it was elevated, they then checked to see what type of White Cell was elevated. I did not feel any symptoms, which made things even more confusing for the docs, as my numbers were through the roof. (Eosiniphil Count was 11,000 when normal range is 0 - 500).

Glad to hear, Jay. So from now on you will no longer take allopurinol? Any concerns? Besides potassium citrate, that is the only med Daniel has been taking since he was diagnosed at the age of three.