I am a woman w/ AMN, and don't let professional descriptions that say women are "carriers" w/o serious symptoms fool you. My sister at 76 has been wheelchair bound for at least a dozen years; I have been mainly in a wheelchair for 3 years--use a walker for short distances, but because the situation is complicated w/ scoliosis, I have poor balance. I, too, have the jumping legs at night. For years I was able to control it by drinking a small glass of diet tonic water when they jumped. More recently that stopped working, so my dr. put me on ReQuip (which is used for restless-leg syndrome) and it works wonderfully--only I tend to be sleepy the next morning. I also have used physical therapy to strengthen my legs. . . Good luck. You have an excellent attitude.